Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359454 | 0.86 | MEN1 (0.39) | MEN1KMT2AKDM4CTLR2PLA2G10 | |
| SCHEMBL9359448 | 0.86 | MEN1 (0.39) | MEN1KMT2AKDM4CTLR2PLA2G10 | |
| SCHEMBL4824612 | 0.79 | MEN1 (0.48) | MEN1KMT2AKDM4CTLR2PLA2G10 | |
| SCHEMBL12446842 | 0.78 | MEN1 (0.36) | MEN1KMT2ATLR2 | |
| SCHEMBL9452690 | 0.78 | MEN1 (0.36) | MEN1KMT2ATLR2 | |
| SCHEMBL13996384 | 0.78 | PLA2G2A (0.38) | MEN1KMT2AKDM4CTLR2PLA2G10 | |
| SCHEMBL24209614 | 0.77 | MEN1 (0.47) | MEN1KMT2AKDM4CTLR2PLA2G10 | |
| SCHEMBL29302791 | 0.77 | MEN1 (0.35) | MEN1KMT2ATLR2 | |
| SCHEMBL19067484 | 0.77 | KDM4C (0.35) | MEN1KMT2AKDM4C | |
| SCHEMBL21068591 | 0.77 | MEN1 (0.52) | MEN1KMT2AKDM4CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145844-A | Enzyme inhibitors, antiinflammatory agents, analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-09-08 | — | — | US | disclosed |
| US-5030733-A | Analgesics, antiinflammatory agents, phospholipase inhibitor | HOECHST-ROUSSEL PHARMACETICALS INCORPORATED (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0300397-A2 | Hydroxy-, Alkoxy- and Benzyloxy substituted phospholipids, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-01-25 | — | — | EP | disclosed |