Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.45 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.41 |
| ▸ | PARG | Q86W56 | 3/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686573 | 0.81 | GRIN1 (0.42) | GRIN1GRIN2BRIPK3PARGGRM5 | |
| SCHEMBL9686841 | 0.80 | GRIN1 (0.43) | GRIN1GRIN2BRIPK3PARGGRM5 | |
| SCHEMBL9688013 | 0.77 | GRIN1 (0.41) | GRIN1GRIN2BRIPK3PARG | |
| SCHEMBL9685792 | 0.74 | GRM7 (0.37) | GRIN1GRIN2BRIPK3 | |
| SCHEMBL27309285 | 0.70 | NPSR1 (0.53) | ALDH1A1NPSR1PKMTSHRKDM4E | |
| SCHEMBL2361576 | 0.66 | CDYL2 (0.45) | ALDH1A1NPSR1PKMTSHRKDM4E | |
| SCHEMBL7774503 | 0.66 | BRD4 (0.39) | — | |
| SCHEMBL2656695 | 0.63 | P2RX7 (0.40) | GRIN1GRIN2BALDH1A1NPSR1LMNA | |
| SCHEMBL20134274 | 0.63 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL10365163 | 0.62 | CNR2 (0.49) | ALDH1A1NPSR1PKMTSHRSHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296416-B1 | BENZO-ANELLATED CYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5077401-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-4902335-A | Benzo-fused cyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0296416-A1 | Benzo-anellated cyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1988-12-28 | — | — | EP | disclosed |