Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | CDC25A | P30304 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810776 | 0.83 | PARK7 (0.58) | PTPN1MEN1KMT2AL3MBTL1NSD2 | |
| SCHEMBL597656 | 0.79 | MEN1 (0.56) | PTPN1MEN1KMT2AL3MBTL1NSD2 | |
| SCHEMBL25834727 | 0.79 | BACE1 (0.52) | PTPN1MEN1KMT2AL3MBTL1NSD2 | |
| SCHEMBL7912021 | 0.79 | PTPN1 (0.52) | PTPN1MEN1KMT2AL3MBTL1NSD2 | |
| SCHEMBL3275939 | 0.79 | PTPN1 (0.52) | PTPN1MEN1KMT2AL3MBTL1NSD2 | |
| SCHEMBL29525396 | 0.79 | MEN1 (0.56) | PTPN1MEN1KMT2AL3MBTL1NSD2 | |
| SCHEMBL10446630 | 0.79 | PTPN1 (0.52) | PTPN1MEN1KMT2AL3MBTL1NSD2 | |
| SCHEMBL4197326 | 0.79 | PTPN1 (0.52) | PTPN1MEN1KMT2AL3MBTL1NSD2 | |
| SCHEMBL1140705 | 0.79 | MEN1 (0.47) | PTPN1MEN1KMT2AL3MBTL1NSD2 | |
| Hydrochloric Acid SCHEMBL4110169 | 0.78 | MEN1 (0.50) | PTPN1MEN1KMT2AL3MBTL1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145975-A | Parasiticides | THE ROCKEFELLER UNIVERSITY (US) | 1992-09-08 | — | — | US | disclosed |
| US-4942170-A | PARASITICIDES, ANTIPROTOZOA AGENTS | THE ROCKEFELLER UNIVERSITY (US) | 1990-07-17 | — | — | US | disclosed |
| EP-0355279-A2 | Use of nitrogen-containing compounds as antiparasitics, and compositions containing them | DRUG & VACCINE DEVELOPMENT CORPORATION (US) | 1990-02-28 | — | — | EP | disclosed |