P-Xylene

P-Xylene

SCHEMBL9685877

CC(=O)OCc1ccc(COC(C)=O)cc1.Cc1ccc(C)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
MAOB P27338 2/20 0.53
CYP3A4 P08684 1/20 0.51
MMP2 P08253 2/20 0.50
MMP12 P39900 2/20 0.50
AGXT P21549 2/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
MMP1 P03956 1/20 0.50
MMP9 P14780 1/20 0.50
LMNA P02545 1/20 0.48
P2RX4 Q99571 1/20 0.47
PARP10 Q53GL7 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
NAAA Q02083 1/20 0.46
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL873414 1.00 ALDH1A1 (0.67) ALDH1A1MAOBCYP3A4MMP2MMP12
SCHEMBL9687590 0.94 ALDH1A1 (0.60) ALDH1A1MAOBCYP3A4MMP2MMP12
SCHEMBL9686517 0.94 ALDH1A1 (0.60) ALDH1A1MAOBCYP3A4MMP2MMP12
SCHEMBL132773 0.91 ALDH1A1 (0.78) ALDH1A1CYP3A4LMNACA2MAPT
SCHEMBL9685963 0.91 ALDH1A1 (0.56) ALDH1A1MAOBCYP3A4MMP2MMP12
SCHEMBL14230576 0.91 ALDH1A1 (0.56) ALDH1A1MAOBCYP3A4MMP2MMP12
E1501 SCHEMBL28313206 0.90 ALDH1A1 (0.85) ALDH1A1NPC1RAB9ALMNAP2RX4
SCHEMBL24983984 0.89 ALDH1A1 (0.55) ALDH1A1MAOBCYP3A4MMP2MMP12
SCHEMBL14063394 0.89 ALDH1A1 (0.55) ALDH1A1MAOBCYP3A4MMP2MMP12
SCHEMBL15853346 0.86 ALDH1A1 (0.50) ALDH1A1MAOBMMP2MMP12AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5078838-A By electrochemical anodic oxidation of benzyl derivatives in the presence of an aliphatic alcohol BASF AKTIENGESELLSCHAFT (DE) 1992-01-07 US disclosed