SCHEMBL9686517

SCHEMBL9686517

CC(=O)OCc1ccc(-c2ccc(C)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
MAOB P27338 2/20 0.49
CYP3A4 P08684 1/20 0.47
MMP12 P39900 3/20 0.47
MMP2 P08253 2/20 0.46
MMP1 P03956 1/20 0.46
MMP9 P14780 1/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
AGXT P21549 2/20 0.45
P2RX4 Q99571 1/20 0.44
LMNA P02545 1/20 0.44
PARP10 Q53GL7 1/20 0.44
NAAA Q02083 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9687590 1.00 ALDH1A1 (0.60) ALDH1A1MAOBCYP3A4MMP12MMP2
SCHEMBL873414 0.94 ALDH1A1 (0.67) ALDH1A1MAOBCYP3A4MMP12MMP2
P-Xylene SCHEMBL9685877 0.94 ALDH1A1 (0.67) ALDH1A1MAOBCYP3A4MMP12MMP2
SCHEMBL4198688 0.92 ALDH1A1 (0.69) ALDH1A1CYP3A4NPC1RAB9ANAAA
SCHEMBL14063397 0.90 ALDH1A1 (0.50) ALDH1A1MAOBCYP3A4MMP12MMP2
SCHEMBL713413 0.86 ALDH1A1 (0.62) ALDH1A1CYP3A4NPC1RAB9ALMNA
SCHEMBL9684759 0.86 ALDH1A1 (0.46) ALDH1A1MAOBCYP3A4MMP12MMP2
SCHEMBL132773 0.85 ALDH1A1 (0.78) ALDH1A1CYP3A4LMNACA2
SCHEMBL9685963 0.85 ALDH1A1 (0.56) ALDH1A1MAOBCYP3A4MMP12MMP2
SCHEMBL14230576 0.85 ALDH1A1 (0.56) ALDH1A1MAOBCYP3A4MMP12MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10322991-B2 Selective aerobic oxidation of dimethylbiphenyls EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-06-18 US disclosed
US-10287230-B2 Selective aerobic oxidation of dimethylbiphenyls EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-05-14 US disclosed
US-20180179141-A1 SELECTIVE AEROBIC OXIDATION OF DIMETHYLBIPHENYLS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2018-06-28 US disclosed
US-20180179138-A1 SELECTIVE AEROBIC OXIDATION OF DIMETHYLBIPHENYLS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2018-06-28 US disclosed
US-5078838-A By electrochemical anodic oxidation of benzyl derivatives in the presence of an aliphatic alcohol BASF AKTIENGESELLSCHAFT (DE) 1992-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180179138-A1 SELECTIVE AEROBIC OXIDATION OF DIMETHYLBIPHENYLS MSMO1, CYP1B1, CYP1A1 ALDH1A1 58/4885MAOB 180/4885CYP3A4 141/4885
US-20180179141-A1 SELECTIVE AEROBIC OXIDATION OF DIMETHYLBIPHENYLS CYP1B1, MSMO1, CYP1A1 ALDH1A1 25/4885MAOB 55/4885CYP3A4 70/4885
US-10287230-B2 Selective aerobic oxidation of dimethylbiphenyls CYP1B1, MSMO1, CYP1A1 ALDH1A1 25/4885MAOB 55/4885CYP3A4 70/4885
US-10322991-B2 Selective aerobic oxidation of dimethylbiphenyls MSMO1, CYP1B1, CYP1A1 ALDH1A1 58/4885MAOB 180/4885CYP3A4 141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.