SCHEMBL9685932

SCHEMBL9685932

CC(C)(C)OC(=O)n1cc(CC(=O)OCc2ccccc2)c2ccccc21

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.77
EPHX1 P07099 1/20 0.48
ACHE P22303 1/20 0.46
MAPK1 P28482 2/20 0.46
PDE10A Q9Y233 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HTR6 P50406 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
ADAM17 P78536 1/20 0.43
TACR3 P29371 1/20 0.42
PIM1 P11309 1/20 0.40
MARK3 P27448 1/20 0.40
MAP4K2 Q12851 1/20 0.40
CAMK2B Q13554 1/20 0.40
PIM3 Q86V86 1/20 0.40
PIM2 Q9P1W9 1/20 0.40
CCKAR P32238 1/20 0.39
CCKBR P32239 1/20 0.39
OPRD1 P41143 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5740608 0.87 L3MBTL1 (1.00) L3MBTL1EPHX1ACHEPDE10AALDH1A1
SCHEMBL2018732 0.84 L3MBTL1 (0.78) L3MBTL1EPHX1ACHEPDE10AALDH1A1
SCHEMBL29651147 0.84 L3MBTL1 (0.78) L3MBTL1EPHX1ACHEPDE10AALDH1A1
SCHEMBL16398989 0.84 L3MBTL1 (0.61) L3MBTL1EPHX1ACHEPDE10AHTR6
SCHEMBL2882457 0.84 L3MBTL1 (0.73) L3MBTL1EPHX1ACHEPDE10AALDH1A1
SCHEMBL7167252 0.84 L3MBTL1 (0.69) L3MBTL1MAPK1ALDH1A1MEN1KMT2A
SCHEMBL16398958 0.82 L3MBTL1 (0.71) L3MBTL1EPHX1ACHEPDE10AHTR6
SCHEMBL16398371 0.82 L3MBTL1 (0.64) L3MBTL1EPHX1ACHEPDE10AHTR6
SCHEMBL12572728 0.82 L3MBTL1 (0.73) L3MBTL1EPHX1ACHEPDE10AHTR6
SCHEMBL16398819 0.81 L3MBTL1 (0.69) L3MBTL1EPHX1ACHEPDE10AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7678925-B2 Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes AJINOMOTO CO., INC. (JP) 2010-03-16 US disclosed
US-5128164-A Sweeteners for foods and beverages SOUTH AFRICAN INVENTIONS DEVELOPMENT CORPORATION (ZA) 1992-07-07 US disclosed
US-4975298-A Sweetners for foods and beverages SOUTH AFRICAN INVENTIONS DEVELOPMENT CORPORATION (ZA) 1990-12-04 US disclosed