Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TOP1 | P11387 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685110 | 0.81 | HTT (0.69) | HTTKDM4EHSD17B10GAAMAPT | |
| SCHEMBL13666895 | 0.77 | KDM4E (0.62) | HTTKDM4EHSD17B10GAAMAPT | |
| SCHEMBL6688920 | 0.77 | HTT (0.56) | HTTKDM4EHSD17B10GAAMAPT | |
| SCHEMBL8837593 | 0.77 | GAA (0.57) | HTTKDM4EHSD17B10GAAMAPT | |
| SCHEMBL30434021 | 0.76 | HTT (0.67) | HTTKDM4EHSD17B10GAAMAPT | |
| SCHEMBL20398637 | 0.76 | HTT (0.67) | HTTKDM4EHSD17B10GAAMAPT | |
| SCHEMBL12748859 | 0.76 | HTT (0.57) | HTTKDM4EHSD17B10GAAMAPT | |
| Acetomenaphthone SCHEMBL29411342 | 0.76 | HTT (1.00) | HTTKDM4EHSD17B10GAAMAPT | |
| Acetomenaphthone SCHEMBL209382 | 0.76 | HTT (1.00) | HTTKDM4EHSD17B10GAAMAPT | |
| SCHEMBL4185213 | 0.75 | ACHE (0.57) | HTTKDM4EHSD17B10GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122442-A | Water soluble binder; photosensitive compound | HOECHST CELANESE CORPORATION (US) | 1992-06-16 | — | — | US | disclosed |
| US-4436804-A | Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith | AMERICAN HOECHST CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |