SCHEMBL8837593

SCHEMBL8837593

CC(=O)Oc1cccc2c(OC(C)=O)c3c(OC(C)=O)cccc3cc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.57
ALDH1A1 P00352 4/20 0.57
MAPT P10636 3/20 0.57
KDM4E B2RXH2 3/20 0.57
KMT2A Q03164 3/20 0.57
L3MBTL1 Q9Y468 3/20 0.57
BLM P54132 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
POLB P06746 1/20 0.57
APEX1 P27695 1/20 0.57
RECQL P46063 1/20 0.57
HTT P42858 2/20 0.51
MAPK1 P28482 2/20 0.46
HSD17B10 Q99714 3/20 0.44
TP53 P04637 1/20 0.44
PTGS1 P23219 2/20 0.42
PGR P06401 1/20 0.42
TOP1 P11387 2/20 0.40
MEN1 O00255 2/20 0.40
MCL1 Q07820 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triacetoxyanthrene SCHEMBL9119527 0.85 ALDH1A1 (0.65) GAAALDH1A1MAPTKDM4EKMT2A
SCHEMBL6001768 0.79 ALDH1A1 (0.51) GAAALDH1A1MAPTKDM4EKMT2A
SCHEMBL8837615 0.78 KMT2A (0.55) GAAMAPTKMT2ATDP1POLB
SCHEMBL7712652 0.78 MAPT (0.46) GAAALDH1A1MAPTKDM4EKMT2A
SCHEMBL9685967 0.77 HTT (0.60) GAAALDH1A1MAPTKDM4EKMT2A
Alpha-Naphthylacetate SCHEMBL76633 0.77 ALDH1A1 (0.66) GAAALDH1A1MAPTKDM4EKMT2A
Alpha-Naphthylacetate SCHEMBL29372782 0.77 ALDH1A1 (0.66) GAAALDH1A1MAPTKDM4EKMT2A
SCHEMBL2680702 0.77 ALDH1A1 (0.55) GAAALDH1A1MAPTKDM4EKMT2A
SCHEMBL8756253 0.76 ESR1 (0.46) GAAMAPTKMT2APOLBHSD17B10
SCHEMBL8756234 0.76 SLC2A1 (0.58) GAAMAPTKMT2APOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5677112-A USING AN ANTHRACENE COMPOUND WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1997-10-14 US disclosed
US-5576359-A ANTHRACENE DERIVATIVE, SOLVENT, COMPOUND CONTAINING GLYCIDYL GROUPS WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1996-11-19 US disclosed
EP-0636941-B1 Deep ultraviolet absorbent and its use in pattern formation WAKO PURE CHEM IND LTD (JP) 1996-03-20 EP disclosed
EP-0636941-A1 Deep ultraviolet absorbent and its use in pattern formation WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1995-02-01 EP disclosed