Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.67 |
| ▸ | S100A4 | P26447 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26115802 | 0.83 | TTR (0.61) | TTRS100A4MAPTMITFPTPRC | |
| SCHEMBL9423356 | 0.81 | S100A4 (0.57) | TTRS100A4MAPTLMNAMITF | |
| SCHEMBL8668950 | 0.77 | ELANE (0.53) | TTRS100A4MAPTLMNAHTT | |
| SCHEMBL2599394 | 0.75 | S100A4 (1.00) | TTRS100A4MAPTLMNAHTT | |
| SCHEMBL9423385 | 0.75 | S100A4 (0.93) | TTRS100A4MAPTLMNAHTT | |
| SCHEMBL8014885 | 0.75 | S100A4 (0.86) | TTRS100A4MAPTLMNAPTPRC | |
| SCHEMBL6259661 | 0.75 | S100A4 (0.93) | TTRS100A4MAPTLMNAHTT | |
| SCHEMBL31268599 | 0.75 | S100A4 (0.86) | TTRS100A4MAPTLMNAPTPRC | |
| SCHEMBL1712674 | 0.73 | TTR (0.88) | TTRMAPTLMNAHTTPTPRC | |
| SCHEMBL10881228 | 0.73 | S100A4 (0.82) | TTRS100A4MAPTPTPRCELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |