Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 13/20 | 0.55 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5534250 | 0.87 | MAPKAPK2 (0.67) | MAPKAPK2PRMT5HTR2AMAPKAPK5HTR2C | |
| SCHEMBL9687220 | 0.85 | MAPKAPK2 (0.50) | MAPKAPK2HTR2AMAPKAPK5HTR2C | |
| SCHEMBL29547973 | 0.81 | MAPKAPK2 (0.67) | MAPKAPK2HTR2AMAPKAPK5HTR2C | |
| SCHEMBL3476628 | 0.81 | MAPKAPK2 (0.67) | MAPKAPK2HTR2AMAPKAPK5HTR2C | |
| SCHEMBL10481507 | 0.74 | MAPKAPK2 (0.67) | MAPKAPK2PRMT5MAPKAPK5GRIN2B | |
| SCHEMBL273473 | 0.74 | MAPKAPK2 (0.67) | MAPKAPK2PRMT5MAPKAPK5GRIN2B | |
| SCHEMBL14948517 | 0.72 | FABP7 (0.35) | MAPKAPK2 | |
| SCHEMBL7436594 | 0.72 | GLA (0.44) | MAPKAPK2HTR2C | |
| SCHEMBL9686034 | 0.72 | ALK (0.44) | — | |
| SCHEMBL6238559 | 0.72 | MAPKAPK2 (0.81) | MAPKAPK2PRMT5MAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4894457-A | BROMINATION, HYDROLYSIS | KAWAKEN FINE CHEMICALS CO., LTD. (JP) | 1990-01-16 | — | — | US | claimed |
| EP-0273321-B1 | 7-BROMO-BETA-CARBOLINE COMPOUND AND METHOD FOR PRODUCING SAME | Kawaken Fine Chemicals Co., Ltd. (JP) | 1992-04-22 | — | — | EP | disclosed |
| US-4894457-A | BROMINATION, HYDROLYSIS | KAWAKEN FINE CHEMICALS CO., LTD. (JP) | 1990-01-16 | — | — | US | disclosed |
| EP-0273321-A1 | 7-Bromo-beta-carboline compound and method for producing same | Kawaken Fine Chemicals Co., Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |