Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617106 | 0.88 | KMT2A (0.51) | KMT2AOPRM1OGFRL1DDB1CRBN | |
| SCHEMBL9687547 | 0.87 | KMT2A (0.45) | ALKKMT2ACFTRGSK3BCDK5 | |
| SCHEMBL9685278 | 0.83 | KMT2A (0.40) | ALKKMT2AOPRM1OGFRL1CFTR | |
| SCHEMBL10465435 | 0.83 | KMT2A (0.43) | ALKKMT2ACFTRMEN1GSK3B | |
| SCHEMBL2708913 | 0.74 | MAPKAPK2 (0.55) | CFTR | |
| SCHEMBL3476660 | 0.72 | OPRM1 (0.40) | KMT2AOPRM1OGFRL1CFTRMEN1 | |
| SCHEMBL9686019 | 0.72 | MAPKAPK2 (0.55) | — | |
| SCHEMBL6238822 | 0.72 | KMT2A (0.51) | KMT2AOPRM1OGFRL1MEN1 | |
| SCHEMBL11318061 | 0.65 | LMNA (0.49) | KMT2AOPRM1OGFRL1MEN1 | |
| SCHEMBL2780429 | 0.64 | MAPKAPK2 (0.45) | KMT2ACFTRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273321-B1 | 7-BROMO-BETA-CARBOLINE COMPOUND AND METHOD FOR PRODUCING SAME | Kawaken Fine Chemicals Co., Ltd. (JP) | 1992-04-22 | — | — | EP | claimed |