SCHEMBL9686248

SCHEMBL9686248

Fc1cc[c]cc1Oc1cccc(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 4/20 0.44
HTR2A P28223 1/20 0.44
KCNH2 Q12809 1/20 0.44
RHEB Q15382 4/20 0.42
SLC6A2 P23975 2/20 0.41
SLC6A3 Q01959 2/20 0.41
AR P10275 1/20 0.40
LMNA P02545 1/20 0.39
HTR1A P08908 1/20 0.39
CYP19A1 P11511 1/20 0.39
EPAS1 Q99814 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
P2RX4 Q99571 1/20 0.36
PTGS1 P23219 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL693499 0.88 SLC6A4 (0.48) SLC6A4HTR2AKCNH2RHEBSLC6A2
SCHEMBL9684517 0.84 SLC6A2 (0.43) SLC6A4SLC6A2SLC6A3HTR1A
SCHEMBL9722870 0.81 MAOB (0.39) LMNAL3MBTL1CYP1A2CYP2C9CYP2C19
SCHEMBL9685597 0.81 MAPT (0.43) LMNAL3MBTL1
SCHEMBL984802 0.81 SLC6A4 (0.47) SLC6A4HTR2AKCNH2RHEBSLC6A2
SCHEMBL9560871 0.80 HTR2A (0.41) SLC6A4HTR2AKCNH2RHEBSLC6A2
SCHEMBL919476 0.80 LTA4H (0.41) SLC6A4HTR2ASLC6A2SLC6A3LMNA
SCHEMBL14662124 0.78 SLC6A4 (0.54) SLC6A4HTR2AKCNH2RHEBSLC6A2
SCHEMBL2261309 0.78 SLC6A4 (0.48) SLC6A4HTR2AKCNH2RHEBSLC6A2
SCHEMBL10776400 0.77 SLC6A4 (0.37) SLC6A4HTR2AKCNH2RHEBSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1044661-C Pesticides, insecticides, miticides and nematocides compositions containing new silanes derivatives HOECHST AG (DE) 1999-08-18 CN disclosed
CN-1032005-C Novel silane derivatives, formulations containing them and their use as pesticides HOECHST AG (DE) 1996-06-12 CN disclosed
CN-1027448-C Heterocyclic neophenan analogs and their use as anti-inflammatory agents HOECHST AG (DE) 1995-01-18 CN disclosed
CN-1091425-A Heterocyclic neophenan analogs, process for their preparation and their use as pesticides HOECHST AG (DE) 1994-08-31 CN disclosed
CN-1025502-C Process for preparing silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1025470-C Pesticide, insecticide and acaricide compositions containing novel silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1025501-C Process for preparing silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1077588-A The agricultural chemicals, insecticide, the acaricidal nematicidal agent composition that contain novel silane derivs HOECHST AG (DE) 1993-10-27 CN disclosed
EP-0288810-B1 HETEROCYCLIC NEOPHANE ANALOGS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-02 EP disclosed
US-5116826-A SILAZANEOPHYL SULFIDES, AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed
EP-0224024-B1 SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-20 EP disclosed
EP-0336199-A1 Azaneophyl and silazaneophyl sulfides, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-11 EP disclosed
US-4864027-A INSECTICIDES, NEMATOCIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-05 US disclosed
EP-0288810-A1 Heterocyclic neophane analogs, processes for their preparation and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-02 EP disclosed
CN-88102112-A Heterocyclic neophenan analogs, process for their preparation and their use as pesticides 1988-10-26 CN disclosed
US-4775664-A INSECTICIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1988-10-04 US disclosed
CN-87102981-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1988-03-02 CN disclosed
EP-0249015-A1 Silane derivatives, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-12-16 EP disclosed
CN-86107292-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1987-07-29 CN disclosed
EP-0224024-A1 Silane derivatives, process for their preparation, agents containing them and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP disclosed