Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441722 | 0.85 | ALDH1A1 (0.38) | SLC6A4HTR2APARP10SLC6A2HTR1A | |
| SCHEMBL921134 | 0.85 | LTA4H (0.41) | LTA4HTSHRSLC6A4HTR2AHRH1 | |
| SCHEMBL9686231 | 0.82 | HTR1A (0.42) | SLC6A4PARP10SLC6A2HTR1ASLC6A3 | |
| SCHEMBL9684517 | 0.82 | SLC6A2 (0.43) | SLC6A4SLC6A2HTR1ASLC6A3KMT2A | |
| SCHEMBL1451604 | 0.82 | LTA4H (0.46) | LTA4HTSHRSLC6A4HRH1SLC6A2 | |
| SCHEMBL9685391 | 0.81 | GAA (0.41) | LTA4HSLC6A4SLC6A2SLC6A3TDP1 | |
| SCHEMBL9685431 | 0.81 | TEAD4 (0.38) | SLC6A4HTR2APARP10SLC6A2SLC6A3 | |
| SCHEMBL9560675 | 0.81 | MAPT (0.38) | SLC6A4PARP10SLC6A2SLC6A3 | |
| SCHEMBL9560871 | 0.81 | HTR2A (0.41) | SLC6A4HTR2ASLC6A2SLC6A3KMT2A | |
| SCHEMBL9686248 | 0.80 | SLC6A4 (0.44) | SLC6A4HTR2ASLC6A2HTR1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108625-A | Spirocyclic derivatives | 克罗诺斯治疗有限公司 | 2017-08-29 | — | — | CN | claimed |
| JP-6008256-B2 | — | ネピュレ株式会社 | 2016-10-19 | — | — | JP | claimed |
| CN-1138735-C | Process and intermediate compounds for preparation of pesticidal fluoroolefin compounds | 谷 | 2004-02-18 | — | — | CN | claimed |
| US-6407100-B1 | HORTICULTURE, AGRICULTURE, WOOD PRESERVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-18 | — | — | US | claimed |
| EP-0885867-B1 | Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds | BASF AG (DE) | 2001-10-24 | — | — | EP | claimed |
| US-6159973-A | Aromatic amides, their preparation process, the compositions containing them and their use as pesticides | HOECHST SCHERING AGREVO S.A. (FR) | 2000-12-12 | — | — | US | claimed |
| EP-0805795-B1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | HOECHST SCHERING AGREVO SA (FR) | 2000-08-23 | — | — | EP | claimed |
| US-6013837-A | E.G.,4-(2-(3,4,5-TRICHLORO PHENYL) 1-FLUOROCYCLOPROPYL)-N-(2-METHYL PHENYL)BENZAMIDE; PARTICULAR USE AGAINST ARTHROPODS, HELMINTHS AND MOLLUSCS; INSECTICIDES; ACARICIDES; NEMATICIDES; PHOTOSTABILITY; NONTOXIC TO MAMMALS | HOECHST MARION ROUSSEL (FR) | 2000-01-11 | — | — | US | claimed |
| US-5973190-A | Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds | AMERICAN CYANAMID COMPANY (US) | 1999-10-26 | — | — | US | claimed |
| CN-1229647-A | 1,4-diaryl-3-fluoro-2-butene compounds for protecting animals and humans against attach and infestation by arthropod parasites | AMERICAN CYANAMID CO (US) | 1999-09-29 | — | — | CN | claimed |
| EP-0058505-A1 | Preparation of esters containing an alpha-cyano group in the alcohol portion of the esters | FMC Corporation (US) | 1982-08-25 | — | — | EP | claimed |
| US-4344960-A | Combating insects and acarids with 3-(2-chloro-3,3,4,4,4-pentafluoro-1-butenyl)-2,2-dimethyl-cyclopropanecarboxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | claimed |
| US-4323685-A | Preparation of esters | FMC CORPORATION (US) | 1982-04-06 | — | — | US | claimed |
| US-4322535-A | REACTION OF AN ACYL HALIDE, ALDEHYDE, AND CYANIDE SALT USING A CATALYTIC AMPHOTERIC SURFACTANT OF AN AMINO ALKYLSULFONATE | FMC CORPORATION (US) | 1982-03-30 | — | — | US | claimed |
| US-4322534-A | Preparation of esters | FMC CORPORATION (US) | 1982-03-30 | — | — | US | claimed |
| US-4318922-A | INSECTICIDES, ACARICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | claimed |
| US-4317834-A | Combating arthropods with fluorine-substituted spiro-carboxylic acid benzyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-02 | — | — | US | claimed |
| EP-0043492-A2 | 1-Aryl-cyclopropane-1-carboxylic-acid esters, their preparation and their use as insecticides | BAYER AG (DE) | 1982-01-13 | — | — | EP | claimed |
| EP-0040742-A1 | 3-(Chloro-3,3,4,4,4-pentafluoro-1-butenyl)-2,2-dimethylcyclopropanecarboxylic acid esters, process for their preparation and their use in insecticides | BAYER AG (DE) | 1981-12-02 | — | — | EP | claimed |
| US-4279923-A | Combating pests with 3-(2,3-dichloro-3,3-difluoro-prop-1-en-1-yl)-2,2-dimethyl-cyclo-propanecarboxylic acid fluoro-benzyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | claimed |