Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.55 |
| ▸ | MTOR | P42345 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26650487 | 0.81 | GRM4 (0.43) | PIK3CDPIK3CAPIK3CGMTORPDE4D | |
| SCHEMBL11275047 | 0.78 | NCF1 (0.58) | PIK3CDCYP1A2CYP2C9NCF1POLB | |
| SCHEMBL29445436 | 0.73 | CYP1A2 (0.56) | PIK3CDPIK3CAPIK3CGMTORCYP1A2 | |
| SCHEMBL1551043 | 0.73 | CYP1A2 (0.56) | PIK3CDPIK3CAPIK3CGMTORCYP1A2 | |
| Tert-Butyl Formate SCHEMBL27585349 | 0.71 | HTR2C (0.43) | PIK3CDNCF1 | |
| SCHEMBL3239336 | 0.71 | PIK3CA (0.52) | PIK3CDPIK3CAPIK3CGMTORCYP1A2 | |
| SCHEMBL27272553 | 0.71 | PIK3CA (0.62) | PIK3CDPIK3CAPIK3CGMTORPOLB | |
| SCHEMBL2276716 | 0.71 | PIK3CA (0.62) | PIK3CDPIK3CAPIK3CGMTORPOLB | |
| SCHEMBL25724448 | 0.71 | PIK3CA (0.62) | PIK3CDPIK3CAPIK3CGMTORPOLB | |
| SCHEMBL25277910 | 0.71 | PIK3CD (0.61) | PIK3CDPIK3CAPIK3CGMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62030780-A | — | — | None | — | — | JP | disclosed |
| EP-0198456-B1 | 1,7-NAPHTHYRIDINE DERIVATIVES AND MEDICINAL PREPARATIONS CONTAINING SAME | SS PHARMACEUTICAL CO., LTD. (JP) | 1992-06-10 | — | — | EP | disclosed |
| US-4690924-A | ANTICHOLINERGIC, ANTIINFLAMMATORY; HYPOTENSIVE AND BRONCHODILATOR AGENTS; ANALGESICS; DIURETICS | SS PHARMACEUTICAL CO., LTD. (JP) | 1987-09-01 | — | — | US | disclosed |
| US-4659710-A | 1,7-Naphthyridine derivatives and pharmaceutical compositions | SS PHARMACEUTICAL CO., LTD. (JP) | 1987-04-21 | — | — | US | disclosed |
| JP-S6230780-A | NAPHTHYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAID DERIVATIVE | SS PHARMACEUT CO LTD | 1987-02-09 | — | — | JP | disclosed |
| EP-0198456-A2 | 1,7-Naphthyridine derivatives and medicinal preparations containing same | SS PHARMACEUTICAL CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |