Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.37 |
| ▸ | MTOR | P42345 | 3/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30600701 | 0.81 | GRM4 (0.52) | GRM4HRH4SCN10APDE10AMTOR | |
| SCHEMBL9686406 | 0.81 | PIK3CD (0.55) | PIK3CDPIK3CAPIK3CGMTORPDE4D | |
| SCHEMBL26646371 | 0.78 | SCN10A (0.46) | GRM4SCN10A | |
| SCHEMBL31316098 | 0.78 | SLC6A4 (0.43) | GRM4SCN10AFFAR2 | |
| SCHEMBL26650968 | 0.78 | NOS3 (0.36) | GRM4SCN10APDE10APIK3CAMTOR | |
| SCHEMBL26650584 | 0.78 | NOS3 (0.36) | GRM4SCN10APDE10APIK3CAMTOR | |
| SCHEMBL30748646 | 0.78 | NOS3 (0.36) | GRM4SCN10APDE10APIK3CAMTOR | |
| SCHEMBL26646217 | 0.78 | SLC6A4 (0.43) | GRM4SCN10AFFAR2 | |
| SCHEMBL26650429 | 0.78 | NOS3 (0.41) | SCN10APIK3CAMTORFFAR2NOS3 | |
| SCHEMBL30748575 | 0.78 | GRM4 (0.42) | GRM4HRH4SCN10APDE10AMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524135-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-03-19 | — | — | EP | disclosed |
| CN-119212988-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-12-27 | — | — | CN | disclosed |
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |