SCHEMBL9686451

SCHEMBL9686451

CCc1ccc2c(OC)c3ccccc3c(OC)c2c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.50
MAPK1 P28482 2/20 0.50
ALDH1A1 P00352 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
POLB P06746 1/20 0.42
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
IDO1 P14902 1/20 0.35
CYP2C19 P33261 1/20 0.35
MCL1 Q07820 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
CNR2 P34972 2/20 0.33
GPR55 Q9Y2T6 2/20 0.33
HPGD P15428 2/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
CASP1 P29466 1/20 0.33
RAB9A P51151 1/20 0.33
CASP7 P55210 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29367461 0.81 KDM4E (0.56) KDM4EMAPK1ALDH1A1SMN1; SMN2POLB
SCHEMBL2576344 0.81 KDM4E (0.56) KDM4EMAPK1ALDH1A1SMN1; SMN2POLB
SCHEMBL1618726 0.79 ALDH1A1 (0.58) KDM4EMAPK1ALDH1A1SMN1; SMN2POLB
SCHEMBL8858056 0.74 KDM4E (0.47) KDM4EMAPK1ALDH1A1SMN1; SMN2POLB
SCHEMBL29288062 0.73 KDM4E (0.46) KDM4EMAPK1ALDH1A1SMN1; SMN2POLB
SCHEMBL12797852 0.72 PTGS2 (0.37) KDM4EMAPK1ALDH1A1SMN1; SMN2POLB
SCHEMBL10022717 0.72 ALDH1A1 (0.71) KDM4EMAPK1ALDH1A1SMN1; SMN2POLB
SCHEMBL23457946 0.72 ALDH1A1 (0.64) KDM4EMAPK1ALDH1A1SMN1; SMN2POLB
SCHEMBL14064624 0.72 KDM4E (0.46) KDM4EMAPK1ALDH1A1SMN1; SMN2POLB
SCHEMBL30490817 0.72 KDM4E (0.46) KDM4EMAPK1ALDH1A1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5122442-A Water soluble binder; photosensitive compound HOECHST CELANESE CORPORATION (US) 1992-06-16 US disclosed
EP-0212482-B1 PROCESS FOR OBTAINING NEGATIVE IMAGES FROM POSITIVE PHOTORESISTS HOECHST CELANESE CORPORATION (US) 1989-04-19 EP disclosed
EP-0212482-A2 Process for obtaining negative images from positive photoresists HOECHST CELANESE CORPORATION (US) 1987-03-04 EP disclosed
EP-0061150-B1 LIGHT-SENSITIVE POLYCONDENSATION PRODUCT, PROCESS FOR ITS PREPARATION AND LIGHT-SENSITIVE RECORDING MATERIAL CONTAINING THE SAME AMERICAN HOECHST CORPORATION (US) 1986-10-15 EP disclosed
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 US disclosed
EP-0061150-A1 Light-sensitive polycondensation product, process for its preparation and light-sensitive recording material containing the same AMERICAN HOECHST CORPORATION (US) 1982-09-29 EP disclosed