Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.35 |
| ▸ | DRD3 | P35462 | 6/20 | 0.35 |
| ▸ | HTR1D | P28221 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234275 | 0.83 | DRD2 (0.34) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL2752397 | 0.83 | DRD2 (0.36) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL18204592 | 0.80 | DRD2 (0.32) | DRD2DRD3HTR1D | |
| SCHEMBL14295166 | 0.79 | DRD2 (0.33) | DRD2DRD3HTR1D | |
| SCHEMBL25608459 | 0.79 | DRD2 (0.38) | DRD2DRD3HTR1D | |
| SCHEMBL2691694 | 0.77 | DRD2 (0.34) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL12987411 | 0.77 | DRD2 (0.32) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL16679324 | 0.77 | DRD2 (0.36) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL15247505 | 0.76 | DRD2 (0.33) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL19813572 | 0.75 | CXCR2 (0.34) | DRD2DRD3HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1059528-A | The new carbocyclic analogs of some nucleosides | MERRELL DOW PHARMA (US) | 1992-03-18 | — | — | CN | disclosed |
| EP-0468866-A1 | Novel carbocyclic analogs of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |
| EP-0468119-A1 | Novel carbocyclic analogs of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |