Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686506 | 0.79 | DRD2 (0.35) | DRD2HTR1DDRD3 | |
| SCHEMBL18204592 | 0.76 | DRD2 (0.32) | DRD2HTR1DDRD3CXCR2 | |
| SCHEMBL25608459 | 0.76 | DRD2 (0.38) | DRD2HTR1DDRD3CXCR2 | |
| SCHEMBL19813572 | 0.75 | CXCR2 (0.34) | DRD2HTR1DDRD3CXCR2 | |
| SCHEMBL19816457 | 0.75 | CXCR2 (0.34) | DRD2HTR1DDRD3CXCR2 | |
| SCHEMBL14537415 | 0.75 | CXCR2 (0.33) | DRD2HTR1DDRD3CXCR2 | |
| SCHEMBL24923816 | 0.74 | DRD2 (0.39) | DRD2HTR1DDRD3 | |
| SCHEMBL21294834 | 0.74 | DRD2 (0.36) | DRD2HTR1DDRD3CXCR2 | |
| SCHEMBL21294833 | 0.74 | DRD2 (0.36) | DRD2HTR1DDRD3CXCR2 | |
| SCHEMBL15166713 | 0.73 | BRD4 (0.38) | DRD2HTR1DDRD3CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080032950-A1 | Neurologically-Active Compounds | THE UNIVERSITY OF SYDNEY (AU) | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080032950-A1 | Neurologically-Active Compounds | GABRE, GABRA5, GABRA1 | DRD2 435/4885HTR1D 674/4885DRD3 511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.