Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9634735 | 0.92 | SLC6A9 (0.58) | SLC6A9PKMCHRM5CHRM1KDM4E | |
| SCHEMBL10444904 | 0.88 | SLC6A9 (0.67) | SLC6A9PKMCHRM5CHRM1SMN1; SMN2 | |
| SCHEMBL9685926 | 0.87 | SLC6A9 (0.68) | SLC6A9PKMCHRM5CHRM1KDM4E | |
| SCHEMBL9686512 | 0.87 | SLC6A9 (0.68) | SLC6A9PKMCHRM5CHRM1SMN1; SMN2 | |
| SCHEMBL9685783 | 0.85 | SLC6A9 (0.64) | SLC6A9PKMCHRM5CHRM1KDM4E | |
| SCHEMBL9636330 | 0.84 | SLC6A9 (0.68) | SLC6A9CHRM5CHRM1KDM4EHRH1 | |
| SCHEMBL9635911 | 0.84 | SLC6A9 (0.68) | SLC6A9CHRM5CHRM1KDM4ESMN1; SMN2 | |
| SCHEMBL9634560 | 0.83 | SLC6A9 (0.67) | SLC6A9CHRM5CHRM1KDM4ESMN1; SMN2 | |
| SCHEMBL9635855 | 0.83 | SLC6A9 (0.64) | SLC6A9PKMCHRM5CHRM1KDM4E | |
| SCHEMBL9684705 | 0.82 | SLC6A9 (0.63) | SLC6A9PKMCHRM5CHRM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307014-B1 | ANTI-ALLERGIC 2-(HETEROCYCLYL ALKYL) IMIDAZO PYRIDINES AND 2-(HETEROCYCLYL ALKYL) PURINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-09 | — | — | EP | disclosed |