Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 12/20 | 0.45 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299555 | 0.95 | ABCC9 (0.46) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9300271 | 0.92 | ABCB1 (0.40) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9301067 | 0.91 | ABCB1 (0.39) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9299457 | 0.91 | ABCC9 (0.47) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9300110 | 0.90 | ABCC9 (0.45) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9299978 | 0.88 | KCNE1 (0.32) | ABCC9 | |
| SCHEMBL9300785 | 0.87 | ABCC9 (0.46) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9298697 | 0.86 | ABCC9 (0.51) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9299366 | 0.85 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9300020 | 0.85 | ABCC9 (0.46) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518342-A1 | Chroman derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-12-16 | — | — | EP | disclosed |