SCHEMBL968659

SCHEMBL968659

OCCCC(c1ccccc1)C1CCCO1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 2/20 0.43
HPGD P15428 5/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
PKM P14618 1/20 0.39
CYP2C19 P33261 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GAA P10253 1/20 0.38
HSD11B1 P28845 1/20 0.37
BRD4 O60885 1/20 0.35
ALDH1A1 P00352 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL971319 0.84 SLC6A3 (0.47) SLC6A3HPGDLMNAMEN1HTT
SCHEMBL3381404 0.83 TRPA1 (0.39) SLC6A3HPGDMEN1KMT2ACYP3A4
SCHEMBL10856691 0.82 SLC6A3 (0.38) SLC6A3HPGDLMNAMEN1HTT
SCHEMBL10857502 0.80 SLC6A3 (0.44) SLC6A3HPGDLMNAMEN1HTT
SCHEMBL10857516 0.79 SLC6A3 (0.43) SLC6A3HPGDLMNAMEN1HTT
SCHEMBL3378258 0.77 MEN1 (0.39) SLC6A3MEN1KMT2ACYP3A4CYP2D6
SCHEMBL10860194 0.77 SLC6A3 (0.37) SLC6A3HPGDLMNAMEN1HTT
SCHEMBL28926384 0.74 HPGD (0.49) SLC6A3HPGDLMNAMEN1HTT
SCHEMBL28926378 0.74 HPGD (0.49) SLC6A3HPGDLMNAMEN1HTT
SCHEMBL28926382 0.74 HPGD (0.49) SLC6A3HPGDLMNAMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829897-B1 SUPPORTED NON-METALLOCENE OLEFIN POLYMERIZATION CATALYST, AND PREPARATION AND USE THEREOF YANGZI PETROCHEMICAL COMPANY CO LTD (CN) 2014-12-10 EP disclosed
US-7875568-B2 reacting silica with titanium tetrachloride to obtain a modified carrier, then mixing with a solution of magnesium chloride, filtering, washing, suction and drying, to prepare a composite carriers, used as supports for addition polymerization catalysts, that improve polymer morphology and bulk density YANGZI PETROCHEMICAL COMPANY CO., LTD. (CN) 2011-01-25 US disclosed
US-20080227936-A1 reacting silica with titanium tetrachloride to obtain a modified carrier, then mixing with a solution of magnesium chloride, filtering, washing, suction and drying, to prepare a composite carriers, used as supports for addition polymerization catalysts, that improve polymer morphology and bulk density YANGZI PETROCHEMICAL COMPANY CO., LTD. (CN) 2008-09-18 US disclosed
EP-1829897-A1 SUPPORTED NON-METALLOCENE OLEFIN POLYMERIZATION CATALYST, AND PREPARATION AND USE THEREOF Yangzi Petrochemical Company Co., Ltd. (CN) 2007-09-05 EP disclosed