Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 14/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017887 | 0.83 | CYP1A2 (0.39) | HTR2ASLC6A4 | |
| SCHEMBL10776400 | 0.80 | SLC6A4 (0.37) | HTR2ASLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL9686709 | 0.78 | KMO (0.40) | KMOSCN9AHSP90AA1HTR2ASLC6A4 | |
| SCHEMBL27274901 | 0.76 | CYP1A2 (0.42) | HTR2ASLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL27652302 | 0.75 | LTA4H (0.47) | — | |
| SCHEMBL6746512 | 0.75 | HTR2A (0.42) | SCN9AHTR2ASLC6A4KCNH2 | |
| SCHEMBL10770907 | 0.74 | AR (0.34) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6777000 | 0.73 | CYP1A1 (0.41) | — | |
| SCHEMBL10390674 | 0.71 | TEAD1 (0.41) | SCN9A | |
| SCHEMBL1282538 | 0.70 | KMO (0.49) | KMOHSP90AA1HTR2ASLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288810-B1 | HETEROCYCLIC NEOPHANE ANALOGS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-02 | — | — | EP | disclosed |