Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 5/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687532 | 0.89 | CYP2C9 (0.39) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9686893 | 0.88 | DPP4 (0.46) | CSF1RDPP4CHRM2DRD1PIK3CD | |
| SCHEMBL9687780 | 0.85 | DPP4 (0.40) | CSF1RDPP4CHRM2DRD1KDM4E | |
| SCHEMBL10378901 | 0.85 | DPP4 (0.49) | DPP4CHRM2DRD1KDM4EABCC4 | |
| Hydrochloric Acid SCHEMBL10916126 | 0.84 | DPP4 (0.49) | DPP4CHRM2DRD1KDM4EABCC4 | |
| Hydrochloric Acid SCHEMBL9687485 | 0.84 | DPP4 (0.40) | CSF1RDPP4CHRM2DRD1KDM4E | |
| SCHEMBL10552600 | 0.81 | DPP4 (0.44) | CSF1RDPP4SIRT6CHRM2DRD1 | |
| SCHEMBL10552609 | 0.79 | CSF1R (0.40) | CSF1RDPP4SIRT6PIK3CGKDM4E | |
| SCHEMBL9687524 | 0.77 | LMNA (0.51) | DPP4CHRM2DRD1PIK3CDPIK3R1 | |
| SCHEMBL9687605 | 0.76 | KDM4E (0.51) | DPP4CHRM2DRD1PIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187376-A2 | 6,7-Disubstituted 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids | BAYER AG (DE) | 1986-07-16 | — | — | EP | claimed |
| EP-0187376-B1 | 6,7-DISUBSTITUTED 1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |
| EP-0187376-A2 | 6,7-Disubstituted 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |