Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 6/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686897 | 0.89 | CSF1R (0.37) | LMNAKDM4EHSD17B10DPP4CHRM2 | |
| SCHEMBL9687524 | 0.88 | LMNA (0.51) | CYP2C9LMNAATP6V1B2TBXA2REDNRA | |
| SCHEMBL9686958 | 0.85 | LMNA (0.41) | CYP2C9LMNAATP6V1B2TBXA2REDNRA | |
| SCHEMBL9687448 | 0.85 | LMNA (0.55) | CYP2C9LMNAATP6V1B2TBXA2REDNRA | |
| SCHEMBL10806005 | 0.81 | ALDH1A1 (0.55) | CYP2C9LMNACYP1A2KDM4EALDH1A1 | |
| SCHEMBL11445743 | 0.77 | CASP1 (0.47) | CYP2C9LMNACYP1A2KDM4EALDH1A1 | |
| SCHEMBL9686893 | 0.77 | DPP4 (0.46) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10377709 | 0.76 | DPP4 (0.51) | CYP2C9LMNAATP6V1B2TBXA2REDNRA | |
| SCHEMBL10377270 | 0.75 | DPP4 (0.50) | CYP2C9LMNAATP6V1B2TBXA2REDNRA | |
| SCHEMBL10377338 | 0.75 | DPP4 (0.50) | CYP2C9LMNAATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187376-A2 | 6,7-Disubstituted 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids | BAYER AG (DE) | 1986-07-16 | — | — | EP | claimed |
| EP-0187376-B1 | 6,7-DISUBSTITUTED 1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |
| EP-0187376-A2 | 6,7-Disubstituted 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |