Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292047 | 0.79 | ALDH1A1 (0.50) | CA2CA1CA5ACA9ALDH1A1 | |
| SCHEMBL5080120 | 0.79 | ALDH1A1 (0.43) | CA2CA1CA5ACA9ALDH1A1 | |
| SCHEMBL28655742 | 0.79 | ALDH1A1 (0.43) | CA2CA1CA5ACA9ALDH1A1 | |
| SCHEMBL30503531 | 0.79 | ALDH1A1 (0.50) | CA2CA1CA5ACA9ALDH1A1 | |
| SCHEMBL9275642 | 0.79 | ALDH1A1 (0.43) | CA2CA1CA5ACA9ALDH1A1 | |
| Formaldehyde SCHEMBL27583784 | 0.78 | ALDH1A1 (0.44) | CA2CA1CA5ACA9ALDH1A1 | |
| Phosphine SCHEMBL15251933 | 0.77 | ALDH1A1 (0.48) | CA2CA1CA5ACA9ALDH1A1 | |
| SCHEMBL18378660 | 0.75 | CA2 (0.45) | CA2CA1CA5ACA9ALDH1A1 | |
| SCHEMBL6683583 | 0.75 | CA2 (0.41) | CA2CA1CA5ACA9ALDH1A1 | |
| SCHEMBL22782197 | 0.75 | CA2 (0.41) | CA2CA1CA5ACA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |