Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687520 | 0.89 | ALDH1A1 (0.61) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL10072797 | 0.83 | MAPK1 (0.55) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL9522714 | 0.83 | SMN1; SMN2 (0.46) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL9377738 | 0.81 | MAPK1 (0.42) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL3940043 | 0.79 | MAPK1 (0.50) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL30168125 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL3150784 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL8547885 | 0.77 | MAPK1 (0.49) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL50326 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL9687384 | 0.77 | BRD4 (0.47) | ALDH1A1HPGDMAPK1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |