Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940043 | 0.90 | MAPK1 (0.50) | MAPK1ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL8547885 | 0.89 | MAPK1 (0.49) | MAPK1ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL9608995 | 0.87 | PKM (0.57) | MAPK1ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL9214730 | 0.87 | MAPK1 (0.47) | MAPK1ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL24603810 | 0.87 | ALDH1A1 (0.48) | MAPK1ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL22289678 | 0.84 | SIRT2 (0.51) | MAPK1ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL9686952 | 0.83 | ALDH1A1 (0.53) | MAPK1ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL12408064 | 0.82 | MAPT (0.51) | MAPK1ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL11873517 | 0.79 | HSD17B10 (0.43) | MAPK1ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL29595480 | 0.79 | HSD17B10 (0.43) | MAPK1ALDH1A1HPGDTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077990-A1 | Alkene Aziridination | NATIONAL SCIENCE FOUNDATION | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077990-A1 | Alkene Aziridination | AZI2, PPOX, GLI2 | MAPK1 3037/4885ALDH1A1 890/4885HPGD 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.