Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687604 | 0.85 | CYP2C19 (0.41) | CYP2C19GRIK1GRIK2 | |
| SCHEMBL9688048 | 0.79 | CYP2C19 (0.42) | CYP2C19 | |
| SCHEMBL1934586 | 0.75 | CYP2C19 (0.47) | CYP2C19MME | |
| SCHEMBL9687663 | 0.74 | — | — | |
| SCHEMBL4580987 | 0.71 | CYP2C19 (0.46) | CYP2C19MEN1ALDH1A1KMT2AMME | |
| SCHEMBL1055977 | 0.71 | — | — | |
| SCHEMBL27689461 | 0.70 | CYP2C19 (0.45) | CYP2C19 | |
| SCHEMBL16700278 | 0.70 | CYP2C19 (0.45) | CYP2C19 | |
| Bicarbonate SCHEMBL165177 | 0.70 | GRIK1 (0.47) | PTPN7RECQLTDP1KDM4EMEN1 | |
| Bicarbonate SCHEMBL15968046 | 0.70 | GRIK1 (0.47) | PTPN7RECQLTDP1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124343-A | Carbacyclins, process for the preparation thereof, and use thereof as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-06-23 | — | — | US | disclosed |