Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686990 | 0.85 | CYP2C19 (0.38) | CYP2C19GRIK1GRIK2 | |
| SCHEMBL9688048 | 0.82 | CYP2C19 (0.42) | CYP2C19FFAR3 | |
| SCHEMBL1934586 | 0.78 | CYP2C19 (0.47) | CYP2C19FFAR3 | |
| SCHEMBL1055977 | 0.73 | — | — | |
| SCHEMBL27689461 | 0.72 | CYP2C19 (0.45) | CYP2C19 | |
| SCHEMBL16700278 | 0.72 | CYP2C19 (0.45) | CYP2C19 | |
| SCHEMBL9688075 | 0.72 | — | — | |
| SCHEMBL11381914 | 0.72 | CYP2C19 (0.55) | CYP2C19 | |
| SCHEMBL9825067 | 0.71 | GRIK1 (0.47) | CYP2C19GRIK1GRIK2 | |
| SCHEMBL4580987 | 0.70 | CYP2C19 (0.46) | CYP2C19FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124343-A | Carbacyclins, process for the preparation thereof, and use thereof as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-06-23 | — | — | US | disclosed |