Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATP4A | P20648 | 1/20 | 0.46 |
| ▸ | ATP4B | P51164 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9686490 | 0.99 | KDM4E (0.62) | KDM4EALDH1A1GLAHTTMAPT | |
| SCHEMBL9684850 | 0.85 | ATP4A (0.52) | KDM4EALDH1A1GLAHTTMAPT | |
| SCHEMBL9684754 | 0.78 | KDM4E (0.51) | KDM4E | |
| SCHEMBL9685620 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1GLAHTTLMNA | |
| SCHEMBL9685760 | 0.77 | KDM4E (0.80) | KDM4EALDH1A1GLAHTTLMNA | |
| SCHEMBL9685928 | 0.77 | KDM4E (0.80) | KDM4EALDH1A1GLAHTTLMNA | |
| SCHEMBL7958379 | 0.72 | GSK3A (0.56) | KDM4EALDH1A1HTTMAPTLMNA | |
| SCHEMBL9685162 | 0.71 | KDM4E (0.86) | KDM4EALDH1A1GLAHTTLMNA | |
| SCHEMBL7488879 | 0.71 | KDM4E (0.66) | KDM4EALDH1A1GLAHTTLMNA | |
| SCHEMBL7496616 | 0.69 | KDM4E (0.62) | KDM4EALDH1A1GLAHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307078-B1 | QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1992-08-26 | — | — | EP | claimed |