SCHEMBL9687211

SCHEMBL9687211

CCOC1CO[PH](=O)OC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL733705 0.72
SCHEMBL9687561 0.69
SCHEMBL2166031 0.69
SCHEMBL9687206 0.68 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2
SCHEMBL1935541 0.67
SCHEMBL28100622 0.65 ALDH1A1 (0.30) ALDH1A1SMN1; SMN2
SCHEMBL27761736 0.65 CA2 (0.32)
SCHEMBL12855787 0.65 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2
SCHEMBL184319 0.65
SCHEMBL14341674 0.63 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0159040-B1 PYRIDINE DERIVATIVES AND PRODUCTION THEREOF NIPPON SHINYAKU COMPANY, LIMITED (JP) 1992-12-09 EP disclosed
US-5036059-A Hypotensive agents, vasodilators NIPPON SHINYAKU COMPANY, LIMITED (JP) 1991-07-30 US disclosed
EP-0159040-A2 Pyridine derivatives and production thereof NIPPON SHINYAKU COMPANY, LIMITED (JP) 1985-10-23 EP disclosed