Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | FBP1 | P09467 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | MC5R | P33032 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | CCR2 | P41597 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11882398 | 0.93 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HPGDFBP1ALOX15 | |
| SCHEMBL11873171 | 0.87 | ALDH1A1 (0.64) | ALDH1A1HSD17B10HPGDFBP1ALOX15 | |
| SCHEMBL9687490 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HSD17B10HPGDFBP1ALOX15 | |
| SCHEMBL8516465 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HSD17B10HPGDFBP1ALOX15 | |
| SCHEMBL29392402 | 0.83 | ALDH1A1 (0.74) | ALDH1A1HSD17B10HPGDFBP1ALOX15 | |
| SCHEMBL637062 | 0.83 | ALDH1A1 (0.74) | ALDH1A1HSD17B10HPGDFBP1ALOX15 | |
| SCHEMBL11870242 | 0.80 | RAB9A (0.60) | ALDH1A1HSD17B10HPGDFBP1ALOX15 | |
| SCHEMBL11874629 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HPGDFBP1ALOX15 | |
| SCHEMBL11877687 | 0.78 | SMN1; SMN2 (0.67) | ALDH1A1HSD17B10HPGDFBP1ALOX15 | |
| SCHEMBL11872299 | 0.77 | ALDH1A1 (0.60) | ALDH1A1HSD17B10HPGDFBP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124450-A | Reacting solution of 2-mercaptothiazole, saturated secondary heterocyclic amine, sulfur in presence of oxygen, ammonia, copper or cerium catalyst | AKZO N.V. (NL) | 1992-06-23 | — | — | US | disclosed |
| EP-0481366-A1 | Process for the preparation of 2-Aminodithiothiazoles and 2-Aminotrithiothiazoles | Akzo Nobel N.V. (NL) | 1992-04-22 | — | — | EP | disclosed |