Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1300013 | 0.86 | HPGD (0.63) | MAPTLMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL9687632 | 0.86 | MAPT (0.67) | MAPTLMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL11614404 | 0.86 | ALDH1A1 (0.70) | MAPTLMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL7819820 | 0.85 | MAPT (0.56) | MAPTLMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL6334067 | 0.85 | MAPT (0.71) | MAPTLMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL6334069 | 0.85 | MAPT (0.71) | MAPTLMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL5490905 | 0.85 | ALDH1A1 (0.65) | MAPTLMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL19718034 | 0.84 | MAPT (0.54) | MAPTLMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL4701157 | 0.83 | MAPT (0.59) | MAPTLMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL6926436 | 0.83 | MAPT (0.62) | MAPTLMNANPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105288724-B | Utilize the method for curcumin derivate processing titania nanotube | 广西中医药大学 | 2018-04-06 | — | — | CN | claimed |
| EP-2245132-B1 | ENCAPSULATED BENEFIT AGENT | UNILEVER PLC NO 41424 (GB) | 2017-10-18 | — | — | EP | claimed |
| CN-105288724-A | Method for treatment of titanium dioxide nanotubes with curcumin derivative | UNIV GUANGXI CHINESE MEDICINE | 2016-02-03 | — | — | CN | claimed |
| EP-2245132-A1 | ENCAPSULATED BENEFIT AGENT | Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) | 2010-11-03 | — | — | EP | claimed |
| WO-2009103576-A1 | ENCAPSULATED BENEFIT AGENT | UNILEVER PLC (GB) | 2009-08-27 | — | — | WO | claimed |
| CN-105288724-B | Utilize the method for curcumin derivate processing titania nanotube | 广西中医药大学 | 2018-04-06 | — | — | CN | disclosed |
| EP-2245132-B1 | ENCAPSULATED BENEFIT AGENT | UNILEVER PLC NO 41424 (GB) | 2017-10-18 | — | — | EP | disclosed |
| CN-105288724-A | Method for treatment of titanium dioxide nanotubes with curcumin derivative | UNIV GUANGXI CHINESE MEDICINE | 2016-02-03 | — | — | CN | disclosed |
| CN-101111483-B | IGF-1R inhibitors | KYOWA HAKKO KIRIN CO.,LTD. (JP) | 2011-12-14 | — | — | CN | disclosed |
| EP-2245132-A1 | ENCAPSULATED BENEFIT AGENT | Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) | 2010-11-03 | — | — | EP | disclosed |
| US-7605272-B2 | IGF-1R inhibitor | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-10-20 | — | — | US | disclosed |
| WO-2009103576-A1 | ENCAPSULATED BENEFIT AGENT | UNILEVER PLC (GB) | 2009-08-27 | — | — | WO | disclosed |
| CN-101111483-A | IGF-1R inhibitors | KYOWA HAKKO KOGYO KK (JP) | 2008-01-23 | — | — | CN | disclosed |
| EP-1847532-A1 | IGF-1R INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |
| CN-1034120-C | Pyridine derivatives | ZENECA LTD (GB) | 1997-02-26 | — | — | CN | disclosed |
| EP-0365328-B1 | Pyridine derivatives | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| EP-0534246-A2 | Benzylamine derivatives and medicines with antiarrhythmic activity containing them | BASF Aktiengesellschaft (DE) | 1993-03-31 | — | — | EP | disclosed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | disclosed |
| EP-0209701-B1 | 1,4-DIHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | BAYER AG (DE) | 1989-08-16 | — | — | EP | disclosed |
| EP-0010063-A2 | Process for the preparation of furanyl-benzazoles | CIBA-GEIGY AG (CH) | 1980-04-16 | — | — | EP | disclosed |