Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746598 | 0.70 | ALDH1A1 (0.30) | ALDH1A1TP53ALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL5953448 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TP53ALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL8405901 | 0.69 | LMNA (0.42) | — | |
| SCHEMBL987513 | 0.66 | LMNA (0.33) | — | |
| SCHEMBL9337430 | 0.65 | ALDH1A1 (0.44) | ALDH1A1TP53ALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL9639825 | 0.64 | — | — | |
| SCHEMBL8018496 | 0.64 | — | — | |
| SCHEMBL8025152 | 0.64 | — | — | |
| SCHEMBL9639822 | 0.64 | — | — | |
| SCHEMBL8402346 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175709-B1 | SUBSTANCE, COMPOSITION OF MATTER AND METHOD OF USING SAME | ARIZONA BOARD OF REGENTS (US) | 1992-07-22 | — | — | EP | disclosed |