Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782794 | 0.85 | CYSLTR1 (0.50) | PDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL8800412 | 0.84 | CYSLTR1 (0.49) | PDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL15474905 | 0.81 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPTHTTTSHR | |
| SCHEMBL17991068 | 0.80 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTHTTTSHR | |
| SCHEMBL16516354 | 0.79 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTHTTTSHR | |
| SCHEMBL16516340 | 0.79 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTHTTTSHR | |
| SCHEMBL9597779 | 0.79 | RAB9A (0.64) | ALDH1A1SMN1; SMN2MAPTHTTTSHR | |
| SCHEMBL10547704 | 0.78 | PDE10A (0.64) | CYP1A2PDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL3271327 | 0.78 | CYSLTR1 (0.69) | PDE10ACYSLTR1CYSLTR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL15066069 | 0.78 | CYSLTR1 (0.50) | CYP1A2PDE10ACYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291916-B1 | DITHIOACETAL COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-5081126-A | QUINOLYL- AND ISOQUINOLYL-METHOXYPHENYL-DITHIOACETYL DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| US-4963576-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS; 5-LIPOXYGENASE INHIBITOR | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0291916-A1 | Dithioacetal compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-23 | — | — | EP | disclosed |