Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689763 | 0.77 | CYP17A1 (0.48) | CYP19A1CYP11B1CYP11B2CYP17A1CYP3A4 | |
| SCHEMBL10464807 | 0.74 | CYP17A1 (0.51) | CYP11B1CYP11B2CYP17A1CYP3A4 | |
| SCHEMBL20229553 | 0.74 | FAAH (0.43) | NPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL21976909 | 0.74 | FAAH (0.43) | NPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL9688353 | 0.73 | CYP19A1 (0.52) | CYP19A1CYP11B1CYP11B2TBXAS1CYP17A1 | |
| SCHEMBL11079263 | 0.72 | CYP19A1 (0.58) | CYP19A1CYP11B1CYP11B2TBXAS1CYP3A4 | |
| SCHEMBL9687706 | 0.72 | CYP17A1 (0.53) | CYP19A1CYP11B1CYP11B2CYP17A1CYP3A4 | |
| SCHEMBL20003881 | 0.71 | GRM4 (0.49) | NPC1RAB9ASMN1; SMN2CYP3A4 | |
| Pyrazine SCHEMBL28254063 | 0.70 | HIF1A (0.41) | ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL85415 | 0.69 | CA12 (0.41) | SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298921-B1 | 1,2-BENZISOXAZOLES AND 1,2-BENZISOTHIAZOLES | CIBA-GEIGY AG (CH) | 1992-12-23 | — | — | EP | disclosed |
| EP-0298921-A1 | 1,2-Benzisoxazoles and 1,2-benzisothiazoles | CIBA-GEIGY AG (CH) | 1989-01-11 | — | — | EP | disclosed |