Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771578 | 1.00 | NR4A2 (0.53) | NR4A2CREBBPGPR84FFAR1NOD2 | |
| SCHEMBL4766917 | 1.00 | NR4A2 (0.53) | NR4A2CREBBPGPR84FFAR1NOD2 | |
| SCHEMBL5881120 | 0.84 | NR4A2 (0.55) | NR4A2CREBBPGPR84FFAR1NOD2 | |
| SCHEMBL6287232 | 0.83 | ALDH1A1 (0.55) | NR4A2CREBBPGPR84FFAR1NOD2 | |
| SCHEMBL6287227 | 0.83 | NR4A2 (0.54) | NR4A2CREBBPGPR84FFAR1NOD2 | |
| SCHEMBL1327936 | 0.83 | GPR84 (0.54) | NR4A2CREBBPGPR84FFAR1NOD2 | |
| SCHEMBL29800817 | 0.83 | GPR84 (0.54) | NR4A2CREBBPGPR84FFAR1NOD2 | |
| SCHEMBL9583795 | 0.82 | NR4A2 (0.53) | NR4A2CREBBPGPR84FFAR1NOD2 | |
| SCHEMBL3334190 | 0.82 | NR4A2 (0.53) | NR4A2CREBBPGPR84FFAR1NOD2 | |
| SCHEMBL3971936 | 0.81 | MEN1 (0.56) | GPR84FFAR1NOD2MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |