Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174246 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL16809364 | 0.67 | PDE2A (0.33) | ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL22612674 | 0.65 | ALDH1A1 (0.35) | ALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL15897986 | 0.65 | PDE2A (0.34) | ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10986689 | 0.64 | ALDH1A1 (0.49) | ALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL7016435 | 0.64 | — | — | |
| SCHEMBL18558813 | 0.64 | — | — | |
| SCHEMBL6162687 | 0.64 | MAPK1 (0.38) | ALDH1A1GAA | |
| SCHEMBL7616115 | 0.61 | NPC1 (0.34) | GAA | |
| SCHEMBL13567222 | 0.60 | HTT (0.33) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3947459-A | FROM ALKALI SALT OF MERCAPTOTHIAZOLES, AMINES AND BLEACH | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-03-30 | — | — | US | claimed |
| US-5124450-A | Reacting solution of 2-mercaptothiazole, saturated secondary heterocyclic amine, sulfur in presence of oxygen, ammonia, copper or cerium catalyst | AKZO N.V. (NL) | 1992-06-23 | — | — | US | disclosed |
| EP-0481366-A1 | Process for the preparation of 2-Aminodithiothiazoles and 2-Aminotrithiothiazoles | Akzo Nobel N.V. (NL) | 1992-04-22 | — | — | EP | disclosed |