Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRE | P78334 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.30 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.30 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4160261 | 0.78 | ALDH1A1 (0.40) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11308300 | 0.72 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL11633106 | 0.72 | MEN1 (0.36) | ALDH1A1 | |
| SCHEMBL27417193 | 0.71 | AGER (0.36) | — | |
| SCHEMBL5138095 | 0.67 | HRH3 (0.41) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11129707 | 0.67 | MEN1 (0.33) | ALDH1A1 | |
| SCHEMBL28292288 | 0.66 | AGER (0.53) | — | |
| SCHEMBL5909779 | 0.65 | HRH2 (0.35) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11386954 | 0.64 | SLC5A2 (0.33) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1719258 | 0.64 | ALDH1A1 (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3947459-A | FROM ALKALI SALT OF MERCAPTOTHIAZOLES, AMINES AND BLEACH | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-03-30 | — | — | US | claimed |
| EP-1205472-B1 | Process for the preparation of dithiazolyldisulfides | BAYER AG (DE) | 2005-01-26 | — | — | EP | disclosed |
| US-6610857-B2 | Oxidation of 2-mercaptothiazoles with peroxidic compounds in an aqueous suspension | BAYER AKTIENGESELLSCHAFT (DE) | 2003-08-26 | — | — | US | disclosed |
| EP-1205472-A1 | Process for the preparation of dithiazolyldisulfides | BAYER AG (DE) | 2002-05-15 | — | — | EP | disclosed |
| US-20020055640-A1 | Process for the production of dithiazolyl disulfides | LANXESS DEUTSCHLAND GMBH (DE) | 2002-05-09 | — | — | US | disclosed |
| US-6248896-B1 | APPROPRIATELY SUBSTITUTED 2-MERCAPTOTHIAZOLE IS OXIDIZED WITH OXYGEN OR AN OXYGEN-CONTAINING GAS IN THE PRESENCE OF A SOLVENT AND A TERTIARY AMINE AND IRON HEMIPORPHYRAZINE. | BAYER AKTIENGESELLSCHAFT (DE) | 2001-06-19 | — | — | US | disclosed |
| US-6124467-A | Process for the preparation of dithiazolyl disulfides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-09-26 | — | — | US | disclosed |
| EP-1008591-A1 | Process for the preparation of dithiazolyldisulfides | Bayer Aktiengesellschaft (DE) | 2000-06-14 | — | — | EP | disclosed |
| US-5124450-A | Reacting solution of 2-mercaptothiazole, saturated secondary heterocyclic amine, sulfur in presence of oxygen, ammonia, copper or cerium catalyst | AKZO N.V. (NL) | 1992-06-23 | — | — | US | disclosed |
| EP-0481366-A1 | Process for the preparation of 2-Aminodithiothiazoles and 2-Aminotrithiothiazoles | Akzo Nobel N.V. (NL) | 1992-04-22 | — | — | EP | disclosed |
| US-4558135-A | AMMONIA CATALYST | AKZONA INCORPORATED (US) | 1985-12-10 | — | — | US | disclosed |
| US-4307236-A | BY CATALYTIC OXIDATION OF 2-MERCAPTO THIAZOLES | AKZONA INCORPORATED (US) | 1981-12-22 | — | — | US | disclosed |
| US-4182873-A | AMINATION OF MERCAPTO THIAZOLE OR DISULFIDE | RHONE-POULENC S.A. (FR) | 1980-01-08 | — | — | US | disclosed |
| US-3947459-A | FROM ALKALI SALT OF MERCAPTOTHIAZOLES, AMINES AND BLEACH | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020055640-A1 | Process for the production of dithiazolyl disulfides | GPX4, PRDX3, PRDX2 | ALDH1A1 507/4885GABRP 3891/4885GABRD 3873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.