Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.51 |
| ▸ | MAOB | P27338 | 9/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832862 | 0.87 | ALDH1A1 (0.56) | GRM5MAOBMAOASMN1; SMN2ALDH1A1 | |
| Alcohol SCHEMBL8562852 | 0.84 | GRM5 (0.59) | GRM5MAOBMAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL27819568 | 0.82 | GRM5 (0.50) | GRM5MAOBMAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL769313 | 0.82 | NPC1 (0.54) | GRM5MAOBMAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL74946 | 0.81 | GRM5 (0.49) | GRM5MAOBMAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL12216209 | 0.81 | GRM5 (0.51) | GRM5MAOBMAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL15092129 | 0.80 | GRM5 (0.53) | GRM5MAOBMAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL15113862 | 0.78 | GRM5 (0.46) | GRM5MAOBMAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL670311 | 0.77 | GRM5 (0.47) | GRM5MAOBMAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL29446216 | 0.77 | GRM5 (0.47) | GRM5MAOBMAOASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517065-A1 | Tetracyclic beta-lactam antibiotics and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-09 | — | — | EP | disclosed |