Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690546 | 0.99 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2MEN1MAPTLMNA | |
| SCHEMBL9690353 | 0.98 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2MEN1MAPTLMNA | |
| SCHEMBL9689332 | 0.96 | MEN1 (0.43) | KMT2ASMN1; SMN2MEN1ELANEPLAU | |
| SCHEMBL9689274 | 0.89 | POLB (0.50) | KMT2ASMN1; SMN2MEN1MAPTLMNA | |
| SCHEMBL9690569 | 0.88 | POLB (0.52) | KMT2ASMN1; SMN2MEN1MAPTLMNA | |
| SCHEMBL9690308 | 0.87 | POLB (0.47) | KMT2ASMN1; SMN2MEN1MAPTLMNA | |
| SCHEMBL9688343 | 0.84 | POLB (0.43) | KMT2AMEN1MAPTPOLBELANE | |
| SCHEMBL7336185 | 0.84 | SMN1; SMN2 (0.44) | KMT2ASMN1; SMN2MEN1MAPTLMNA | |
| SCHEMBL7336821 | 0.83 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2MEN1MAPTLMNA | |
| SCHEMBL7336430 | 0.82 | SMN1; SMN2 (0.44) | KMT2ASMN1; SMN2MEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486702-A1 | PHENYL 4-GUANIDINOBENZOATE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PROTEASE INHIBITOR CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-05-27 | — | — | EP | disclosed |