SCHEMBL9689332

SCHEMBL9689332

N=C(N)Nc1ccc(C(=O)Oc2cc(Cl)cc(OC(=O)C3CC3)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PRSS1 P07477 5/20 0.39
F2 P00734 4/20 0.39
PRSS2 P07478 4/20 0.39
PRSS3 P35030 4/20 0.39
ST14 Q9Y5Y6 3/20 0.39
PLG P00747 3/20 0.38
ELANE P08246 1/20 0.38
RAB9A P51151 1/20 0.38
ACR P10323 1/20 0.37
F10 P00742 1/20 0.36
PLAU P00749 1/20 0.36
PLAT P00750 1/20 0.36
HPGD P15428 1/20 0.35
F12 P00748 1/20 0.35
TMPRSS15 P98073 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9690353 0.96 SMN1; SMN2 (0.42) MEN1KMT2ASMN1; SMN2PRSS1F2
SCHEMBL9688325 0.96 KMT2A (0.42) MEN1KMT2ASMN1; SMN2ELANEPLAU
SCHEMBL9690546 0.95 SMN1; SMN2 (0.42) MEN1KMT2ASMN1; SMN2ELANEPLAU
SCHEMBL9688343 0.88 POLB (0.43) MEN1KMT2APRSS1F2PRSS2
SCHEMBL9690308 0.84 POLB (0.47) MEN1KMT2ASMN1; SMN2PRSS1F2
SCHEMBL9689274 0.84 POLB (0.50) MEN1KMT2ASMN1; SMN2PRSS1F2
SCHEMBL9689323 0.84 KMT2A (0.39) MEN1KMT2ASMN1; SMN2PRSS1F2
SCHEMBL7330280 0.83 KMT2A (0.45) MEN1KMT2ASMN1; SMN2RAB9AHPGD
SCHEMBL7338242 0.83 RAB9A (0.54) MEN1KMT2ASMN1; SMN2ELANERAB9A
SCHEMBL9690569 0.83 POLB (0.52) MEN1KMT2ASMN1; SMN2PRSS1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0486702-A1 PHENYL 4-GUANIDINOBENZOATE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PROTEASE INHIBITOR CONTAINING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-05-27 EP disclosed