Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.40 |
| ▸ | ACR | P10323 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689274 | 0.98 | POLB (0.50) | POLBL3MBTL1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL9690569 | 0.97 | POLB (0.52) | POLBL3MBTL1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL9688343 | 0.95 | POLB (0.43) | POLBKMT2AUSP2MAPTELANE | |
| SCHEMBL9690353 | 0.89 | SMN1; SMN2 (0.42) | POLBL3MBTL1KMT2ASMN1; SMN2HTT | |
| SCHEMBL9688325 | 0.87 | KMT2A (0.42) | POLBL3MBTL1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL9690546 | 0.86 | SMN1; SMN2 (0.42) | POLBKMT2AUSP2SMN1; SMN2HTT | |
| SCHEMBL9689332 | 0.84 | MEN1 (0.43) | KMT2ASMN1; SMN2ELANEPRSS1ACR | |
| SCHEMBL27690177 | 0.79 | PARP10 (0.50) | KMT2ASMN1; SMN2MAPTALDH1A1PRSS1 | |
| SCHEMBL9689323 | 0.79 | KMT2A (0.39) | L3MBTL1KMT2ASMN1; SMN2HTTTDP1 | |
| SCHEMBL9689610 | 0.79 | F9 (0.47) | KMT2APRSS1ACRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486702-A1 | PHENYL 4-GUANIDINOBENZOATE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PROTEASE INHIBITOR CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-05-27 | — | — | EP | disclosed |