Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9023951 | 0.99 | HTR2C (0.55) | HTR2CDRD2DRD4SIGMAR1HTR1A | |
| SCHEMBL9445175 | 0.91 | HTR2C (0.51) | HTR2CDRD2HTR1AHTR7HTR2A | |
| SCHEMBL9445318 | 0.90 | HTR2C (0.56) | HTR2CDRD2DRD4SIGMAR1HTR1A | |
| SCHEMBL9024113 | 0.89 | HTR2C (0.54) | HTR2CDRD2DRD4SIGMAR1HTR1A | |
| SCHEMBL9687660 | 0.88 | HTR2C (0.56) | HTR2CDRD2DRD4SIGMAR1HTR1A | |
| Hydrochloric Acid SCHEMBL9023938 | 0.88 | HTR2C (0.56) | HTR2CDRD2DRD4SIGMAR1HTR1A | |
| SCHEMBL9024282 | 0.87 | HTR7 (0.42) | HTR2CDRD2HTR1AHTR7HTR2A | |
| SCHEMBL9474916 | 0.85 | HTR2C (0.53) | HTR2CDRD2DRD4SIGMAR1ADRA1D | |
| Fumaric Acid SCHEMBL9445247 | 0.85 | HTR2C (0.46) | HTR2CDRD2HTR1AHTR7HTR2A | |
| Maleic Acid SCHEMBL9445239 | 0.85 | HTR2C (0.46) | HTR2CDRD2HTR1AHTR7HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114936-A | Antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-05-19 | — | — | US | claimed |