Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.56 |
| ▸ | DRD4 | P21917 | 6/20 | 0.54 |
| ▸ | DRD2 | P14416 | 6/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9023938 | 0.99 | HTR2C (0.56) | HTR2CDRD4DRD2SIGMAR1ADRA1D | |
| SCHEMBL9024113 | 0.94 | HTR2C (0.54) | HTR2CDRD4DRD2SIGMAR1ADRA1D | |
| SCHEMBL9474916 | 0.93 | HTR2C (0.53) | HTR2CDRD4DRD2SIGMAR1ADRA1D | |
| Hydrochloric Acid SCHEMBL9445171 | 0.93 | HTR2C (0.53) | HTR2CDRD4DRD2SIGMAR1ADRA1D | |
| SCHEMBL9445318 | 0.88 | HTR2C (0.56) | HTR2CDRD4DRD2SIGMAR1ADRA1D | |
| SCHEMBL9688546 | 0.88 | HTR2C (0.56) | HTR2CDRD4DRD2SIGMAR1ADRA1D | |
| Hydrochloric Acid SCHEMBL9023951 | 0.88 | HTR2C (0.55) | HTR2CDRD4DRD2SIGMAR1ADRA1D | |
| SCHEMBL9689848 | 0.86 | NR4A2 (0.41) | HTR2CDRD2SIGMAR1HTR1AHTR2A | |
| SCHEMBL9024747 | 0.86 | HTR2C (0.57) | HTR2CDRD4DRD2SIGMAR1ADRA1D | |
| SCHEMBL9445210 | 0.84 | DCTPP1 (0.39) | DRD2DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114936-A | Antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-05-19 | — | — | US | claimed |