Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690193 | 0.85 | PPARG (0.52) | PPARGAGTR1ACHEAGTR2APLNR | |
| SCHEMBL9530672 | 0.85 | PPARG (0.58) | PPARGAGTR1ACHEAGTR2 | |
| SCHEMBL9336755 | 0.84 | PPARG (0.58) | PPARGAGTR1ACHEAGTR2 | |
| SCHEMBL9690253 | 0.83 | AGTR1 (0.49) | PPARGAGTR1ACHEAGTR2APLNR | |
| SCHEMBL9337738 | 0.83 | PPARG (0.56) | PPARGAGTR1ACHEAGTR2 | |
| SCHEMBL9337685 | 0.81 | PPARG (0.53) | PPARGACHE | |
| SCHEMBL9337063 | 0.80 | PPARG (0.52) | PPARGACHE | |
| SCHEMBL9337129 | 0.80 | PPARG (0.53) | PPARGAGTR1ACHEAGTR2 | |
| SCHEMBL9339313 | 0.80 | AGTR1 (0.53) | PPARGAGTR1ACHEAGTR2 | |
| SCHEMBL9337403 | 0.79 | PPARG (0.53) | PPARGACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500297-A1 | Substituted pyridinones and pyrimidinones as angiotensin II antagonists | FISONS plc (GB) | 1992-08-26 | — | — | EP | disclosed |