Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 15/20 | 0.45 |
| ▸ | CCND1 | P24385 | 15/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688963 | 0.84 | CDK4 (0.43) | CDK4CCND1CDK2HTR2C | |
| SCHEMBL9687990 | 0.82 | HTR2C (0.43) | CDK4CCND1CDK2HTR2C | |
| SCHEMBL9036635 | 0.81 | CDK4 (0.43) | CDK4CCND1CDK2HTR2CNR4A2 | |
| SCHEMBL13763424 | 0.74 | PBRM1 (0.58) | CDK4CCND1ALDH1A1NR4A2CREBBP | |
| SCHEMBL29336534 | 0.73 | CDK4 (0.55) | CDK4CCND1CDK2 | |
| SCHEMBL9690016 | 0.73 | KMT2A (0.48) | CDK4CCND1HTR2CALDH1A1MAPT | |
| SCHEMBL9037086 | 0.72 | CDK4 (0.42) | CDK4CCND1CDK2HTR2CMAPT | |
| SCHEMBL9689717 | 0.72 | CDK4 (0.40) | CDK4CCND1ALDH1A1 | |
| SCHEMBL27275913 | 0.72 | CDK4 (0.58) | CDK4CCND1CDK2HTR2CALDH1A1 | |
| SCHEMBL9242994 | 0.72 | KMT2A (0.47) | CDK4CCND1HTR2CALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507861-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS. | UPJOHN CO (US) | 1992-10-14 | — | — | EP | claimed |