Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 16/20 | 0.43 |
| ▸ | CCND1 | P24385 | 16/20 | 0.43 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687990 | 0.94 | HTR2C (0.43) | CDK4CCND1CDK2HTR2CPBRM1 | |
| SCHEMBL9689717 | 0.88 | CDK4 (0.40) | CDK4CCND1SMN1; SMN2 | |
| SCHEMBL9690016 | 0.86 | KMT2A (0.48) | CDK4CCND1HTR2CNPC1RAB9A | |
| SCHEMBL9037086 | 0.84 | CDK4 (0.42) | CDK4CCND1CDK2HTR2CNPC1 | |
| SCHEMBL9688745 | 0.84 | CDK4 (0.45) | CDK4CCND1CDK2HTR2C | |
| SCHEMBL8985884 | 0.82 | MAPT (0.48) | CDK4CCND1CDK2HTR2CNPC1 | |
| SCHEMBL9038237 | 0.81 | CDK4 (0.41) | CDK4CCND1CDK2HTR2C | |
| SCHEMBL9242994 | 0.81 | KMT2A (0.47) | CDK4CCND1HTR2CNPC1RAB9A | |
| SCHEMBL27275913 | 0.76 | CDK4 (0.58) | CDK4CCND1CDK2HTR2CPBRM1 | |
| SCHEMBL9036372 | 0.76 | HTR2C (0.41) | CDK4CCND1CDK2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507861-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS. | UPJOHN CO (US) | 1992-10-14 | — | — | EP | claimed |