Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687209 | 0.91 | MAPT (0.53) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL16041870 | 0.86 | ABL1 (0.46) | HTR6MAPTSMN1; SMN2POLBCA1 | |
| SCHEMBL31612035 | 0.83 | MAPT (0.54) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL17184370 | 0.83 | MAPT (0.54) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL30202595 | 0.83 | POLB (0.58) | HTR6MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28515255 | 0.83 | POLB (0.58) | HTR6MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9689325 | 0.83 | MAPT (0.63) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL15761760 | 0.82 | MEN1 (0.55) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL14376796 | 0.81 | MAPT (0.61) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL28989431 | 0.80 | HTR6 (0.49) | HTR6MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171748-A | For hypertension, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-15 | — | — | US | disclosed |