Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 11/20 | 0.40 |
| ▸ | CCND1 | P24385 | 11/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037383 | 0.98 | HTR2C (0.41) | HTR2CCDK4CCND1LMNACDK2 | |
| SCHEMBL9038031 | 0.97 | HTR2C (0.41) | HTR2CCDK4CCND1LMNACDK2 | |
| SCHEMBL9038237 | 0.94 | CDK4 (0.41) | HTR2CCDK4CCND1LMNACDK2 | |
| SCHEMBL9038843 | 0.85 | LMNA (0.39) | HTR2CCDK4CCND1LMNACDK2 | |
| SCHEMBL9037181 | 0.85 | KDR (0.45) | HTR2CCDK4CCND1LMNAKDR | |
| SCHEMBL9037640 | 0.83 | KDR (0.43) | CDK4CCND1KDRALDH1A1KMT2A | |
| SCHEMBL9036635 | 0.82 | CDK4 (0.43) | HTR2CCDK4CCND1LMNACDK2 | |
| SCHEMBL9037086 | 0.82 | CDK4 (0.42) | HTR2CCDK4CCND1LMNACDK2 | |
| SCHEMBL9038042 | 0.81 | KDR (0.46) | HTR2CCDK4CCND1LMNAKDR | |
| SCHEMBL9687990 | 0.80 | HTR2C (0.43) | HTR2CCDK4CCND1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507861-B1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | UPJOHN CO (US) | 1996-09-11 | — | — | EP | claimed |
| WO-1991009849-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | claimed |